Periodontal Disease and Alzheimer’s: Understanding the Connection

Alzheimer’s disease is a neurogenerative diseasecharacterized by brain cells shrinking and dying. This shrinking of the brainworsens over time. In the United States, over 6.5 million elderly individualssuffer from Alzheimer’s. Common signs of Alzheimer’s can include forgetfulness,memory decline, and behavioral issues. Over time, these problems can increaseand can significantly impact how an individual functions with day-to-day tasks.Currently, there is no cure for Alzheimer’s. However, there are somemedications that can help manage symptoms in some individuals that aresuffering from the disease.

How Can Oral Infections Affect the Brain?

Periodontal disease, also known as gum disease, is aninfection of the gums and supporting tissues surrounding our teeth. Periodontaldisease has been associated with several systemic health effects, includingdiabetes, heart disease, and even Alzheimer’s disease. The most recent researchhas found potential connections between periodontal disease and Alzheimer’srisks. Recent evidence has suggested that those with periodontal disease havean increased likelihood of developing brain inflammation leading to Alzheimer’s.

Researchers believe that as periodontal bacteria levelsincrease in the oral cavity, they then enter the bloodstream and can travel tothe brain. Once in the brain, bacteria can trigger inflammation responses andaffect blood flow. Amyloid plaques are excess protein globules that build up inthe brain and are a classic biomarker in those with Alzheimer’s. This buildupof plaque in the brain causes cell death and dysfunction. The latest researchstates that excessive plaque bacteria associated with gum disease in the oralcavity could lead to higher levels of amyloid plaque in the brain. Thus, thehigher risk for Alzheimer’s disease in those with poor oral health.

Know When to Get Help

It's crucial to speak with your dental provider if you or afamily member is suffering from periodontal disease and/or Alzheimer’s to treatboth conditions effectively and to be aware of the connections these diseasesshare.